Fig 1: Increased capacity of endothelial cells to proliferate and migrate depends on the agglutinin-dependent activation of TLR3 signaling pathways. (a) CCK8 test for the cell proliferation of the control group, the TLR3 knockout group, the recombinant CLU group, and the TLR3 knockout + recombinant CLU group. (b–c). Transwell migration test for the cell migration of the control group, the TLR3 knockout group, recombinant CLU group, and the TLR3 knockout + recombinant CLU group. *p < 0.05; ns, there was no statistical difference.
Fig 2: Platelet-derived clusterins can lead to increased proliferation and migration of vascular endothelial cells. (a) Experimental results of CCK8 in 100 ng/mL of the human recombinant CLU group and the control group in vascular endothelial cell medium. (b) Statistical results of Transwell migration experiments. (c) Transwell migration assay for cell migration between the recombinant CLU group and the control group. (d) Transwell invasion test for the invasion ability of the recombinant CLU group and the control group. *p < 0.05; ns, there was no statistical difference.
Supplier Page from Abcam for Native Human Clusterin protein